Research into this is ongoing. Rhabdomyolysis initially causes muscle pain and can worsen to cause significant muscle breakdown or kidney failure. In rare cases, it can be fatal. The condition is more common in people who take a statin in combination with another drug that carries rhabdomyolysis risk or raises the level of statin in the blood.
Before prescribing a statin to anyone with liver disease, a doctor should thoroughly discuss the risks and possible benefits. If the liver disease is stable and chronic, taking a low-dose statin may carry greater benefits than risks. If the liver disease is progressive, however, guidelines warn against using statins.
Statins inhibit an enzyme called HMG-CoA reductase, which controls cholesterol production in the liver. The medicine blocks the enzyme, thereby slowing down the cholesterol production process. People usually continue taking statins even after reaching their target cholesterol level to maintain the protection against atherosclerosis.
People usually take statins to reduce high cholesterol and prevent atherosclerosis, lowering the risk of heart disease in the process. A doctor may recommend statins:. Atherosclerosis can develop and form plaques even when blood cholesterol levels are low.
Statins may benefit people who already have atherosclerosis or have a high risk of developing it, even if they do not have high cholesterol levels. Statins are a group of drugs that can reduce high cholesterol, lowering the risk of atherosclerosis and heart problems. Statins typically cause mild side effects, if any, but these drugs can, rarely, cause significant, and even life threatening, adverse effects. Hypothyroidism: Should I take iodine supplements? Hypothyroidism symptoms: Can hypothyroidism cause eye problems?
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Muscle pain, increased blood sugar levels, constipation, nausea, diarrhea, stomach pain, cramps, elevation of liver enzymes. Decrease LDL ; usually reserved for people who have a genetic condition that causes very high LDL levels or people with heart disease who cannot tolerate statins or other cholesterol lowering drugs. Citrate lyase inhibitors Bempedoic acid Nexletol Bempedoic acid-ezetimibe Nexlizet.
Combination cholesterol absorption inhibitor and statin Ezetimibe-simvastatin Vytorin. Stomach pain, fatigue, gas, constipation, abdominal pain, cramps, muscle soreness, pain and weakness. Muscle problems and liver abnormalities are rare, but your doctor may order regular liver function tests. Women who are pregnant or people who have active or chronic liver disease should not take statins.
If you have CVD and are already taking the highest tolerated statin and your LDL-C is still 70 or above, one or more of the following medicines may be prescribed. They all can be taken in combination with a statin. Prevents cholesterol from being absorbed in the intestine. They bind to and inactivate a protein on cells found in the liver to lower LDL bad cholesterol. Some names are alirocumab and evolocumab.
ACL inhibitors work in the liver to block the production of cholesterol. They are used in combination with lifestyle changes and statins to further decrease LDL cholesterol in adults with familial heterozygous hypercholesterolemia and patients with heart disease that need to further lower their LDL. Fibrates are especially good for lowering triglyceride blood fat levels and have a mild LDL-lowering action.
Niacin is a B vitamin that limits the production of blood fats in the liver. Take this only if your doctor has prescribed it. It lowers triglycerides and has mild LDL-lowering action. Niacin side effects may include flushing, itching and upset stomach. Your liver functions may be closely monitored because niacin can cause toxicity. Nonprescription immediate-release forms of niacin usually have the most side effects, especially at higher doses.
Niacin is used cautiously in diabetic patients because it can raise blood sugar levels. Niacin comes in prescription form and as a dietary supplement. That lowers the cholesterol in the blood. Statins are prescription drugs used to lower cholesterol. However, they can have side effects and might not be right for everyone. Learn about….
Statins are a common treatment for high cholesterol. Learn about the latest FDA guidelines and recommendations about the use of statins for this…. Statins are among the most popular medications prescribed in America today, but how do they lower cholesterol? Cholesterol often gets a bad rap. High triglycerides can have many causes, including genetics.
When it's an inherited condition, it's known as familial hypertriglyceridemia. HDL cholesterol removes extra cholesterol and plaque buildup in your arteries.
High cholesterol often has no symptoms, but can lead to serious health issues. Having too many triglycerides in your blood can be harmful and lead to heart disease.
Here are some natural ways to lower your triglycerides. Health Conditions Discover Plan Connect. Statins: The Pros and Cons. Medically reviewed by Gerhard Whitworth, R. What are statins? The benefits of statins. The side effects of statins.
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